Imagine healthy, aging people experimenting with synthetic biology to prevent deterioration, replacing their own cells with inviolable, indefatigable ones. From a Technology Review Q&A conducted by David Ewing Duncan with geneticist George Church, whose new book is entitled Regenesis:
“Technology Review:
When is regeneration likely to happen in humans?
George Church:
There is much to be worked out. But here’s the leap. If you want to accelerate this, you have to pick an intermediate target that doesn’t sound so scary. So you’ll start out with bone marrow patients. And you’re going to basically make a synthetic version of that patient’s bone marrow using IPS, which is going to work much better than the diseased bone marrow. And once this works that’s going to catch on like wildfire. And then you’ll do skin, and then you’ll do every other stem cell you can get.
Technology Review:
Who is going to do this?
George Church:
The only way people are going to get this is through some brave soul. It will start with a sick person, and they will end up getting well, possibly more well than before they got sick. So you didn’t just correct the sickness, you actually did more. And they’ll give testimonials, and someone from the New York Times will interview them, and tell this appealing anecdote.
Technology Review:
Will people who are, say, aging but not yet sick ever be able to use this technology?
George Church:
I don’t consider this medicine, it’s preventive. I expect somebody who is truly brave, who has nothing wrong with them other than maybe the usual aging, saying: ‘I want a bone marrow transplant’, or intestinal, or whatever. And it will gain momentum from there.” (Thanks Next Big Future.)